Medicxi Secures €500 Million for New Fund to Propel Biotechnology Innovation

Medicxi Secures €500 Million for New Fund to Propel Biotechnology Innovation

By USFMNovember 16, 2025

Medicxi, a prominent European life sciences venture capital firm, has successfully closed its oversubscribed Fund V, raising €500 million to invest in biotechnology companies. This new fund aims to build on its prior successes, including significant investments and strategic acquisitions in the biotech sector.

Medicxi, a leading venture capital firm specializing in life sciences, has announced the successful closing of Medicxi V, a substantial €500 million fund aimed at fostering the development of biotechnology companies. The fund was oversubscribed and received backing from both existing limited partners and a select group of new institutional investors, underscoring strong confidence in Medicxi's asset-centric investment model.

Medicxi's track record is impressive, having created 16 new companies and achieved over 20 positive clinical data readouts since its last fundraising effort. Noteworthy investments include successful stakes in companies such as Vaxcyte, Merus, and Abivax. Additionally, Medicxi has made strategic acquisitions, notably ViceBio (now under Sanofi), Versanis Bio (acquired by Eli Lilly), and ProfoundBio (acquired by Genmab), which have collectively realized over $1 billion for the firm’s portfolio.

The strategic rationale behind the launch of Fund V is to continue Medicxi’s commitment to supporting drug developers and entrepreneurs in the biotechnology realm. The fund will focus on nurturing asset-focused companies that are committed to delivering innovative therapies for patients, reflecting a clear alignment with Medicxi’s established investment philosophy.

The investment partners for Fund V are Francesco De Rubertis, Giovanni Mariggi, Nick Williams, and Shyam Masrani, who bring a wealth of experience to the firm’s mission. With this financial backing, Medicxi is poised to expand its influence and support within the biotechnology sector.

Looking ahead, the timeline for deploying the capital from Fund V will unfold as Medicxi identifies promising investment opportunities that align with its strategic goals. While specific regulatory hurdles related to investments or acquisitions were not detailed in the filing, it's typical for firms in the biotechnology investment space to navigate various regulatory considerations as they pursue new ventures.

For shareholders, employees, and the broader market, the establishment of Fund V signifies a robust commitment to innovation in the biotech sector, which may lead to increased market activity as new companies emerge and existing firms expand through Medicxi’s strategic investments. Overall, this fund reinforces Medicxi’s position as a key player in the life sciences venture capital landscape.